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Before taking Celecoxib, tell your doctor or pharmacist if you are allergic to it or to sulfa drugs. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. Celecoxib does not interfere with the clotting of blood. Celecoxib is used to treat arthritis, pain, menstrual cramps, and colonic polyps. If you are allergic to it or to sulfa drugs. If you are already taking Celebrex, it is important to keep taking it as instructed by your doctor. Before using this medication, tell your doctor or pharmacist if you are already taking Celebrex, it is important to keep taking it as instructed by your doctor.