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Prednisolone prevents the release of substances in the body that cause inflammation. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders. Prednisone to Prednisolone is impaired. Prednisolone is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis.